Histaminergic modulation of anesthetic potency of halothane.
نویسندگان
چکیده
منابع مشابه
Dependence of halothane potency on pH.
The effect of halothane on the amplitude and conduction time of the evoked nerve action potential of a mammalian nerve preparation was determined in vitro. The action of 4 per cent v/v halothane on the action potential was measured at three different hydrogen ion concentrations in the Krebs perfusate, namely, pH 6.57, pH 7.40, pH 8.00. Halothane potency, assessed by the depression of the action...
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PURPOSE Halothane offers protection against the reperfusion injury of the myocardium. This study compared sevoflurane with halothane in its potential to modulate the effects of acute severe ischemia and reperfusion on the myocardium. METHODS Experiments were conducted on 25 pigs. Anesthesia consisted of thiopental, vecuronium and fentanyl. The lungs were mechanically ventilated with oxygen an...
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Heart of England NHS Foundation Trust, Birmingham, UK School of Life and Health Sciences, Aston Brain Centre, Aston University, Birmingham, UK Children’s Epilepsy Surgery Programme, The Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK Sobell Department of Motor Neuroscien...
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Encoding for several memory types requires neural changes and the activity of distinct regions across the brain. These areas receive broad projections originating in nuclei located in the brainstem which are capable of modulating the activity of a particular area. The histaminergic system is one of the major modulatory systems, and it regulates basic homeostatic and higher functions including a...
متن کاملCentral histaminergic modulation of vestibular function - a review.
Histaminergic drugs have long been used to treat balance disorders in man, but their mechanisms of action in the vestibular system are poorly understood. In this article we review the current literature on histaminergic neurotransmission in the brain focussing particularly in the brainstem vestibular nuclei, and the role of histamine in brain plasticity during "vestibular compensation", the beh...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1994
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)50207-4